Until recently, aesthetics was concerned with just masking the visible effects of ageing and UV damage with the likes of face lifts and botox. Globally, autologous stem cell-based medical aesthetic treatments are becoming all the rage; their minimally invasive procedures require less downtime and produce more effective and natural results.

Instead, we focus on preventing and repairing damage by employing the natural mechanisms your body already has at its disposal for a better-looking, more effective and longer-lasting solution to your aesthetic needs. All with your own stem cells.

Medical science has demonstrated that adipose-derived mesenchymal stem cells (AdMSC) secretory factors can reverse human skin ageing, whether it be light wrinkles, UV light damage, collagen loss or rough skin). We can repair the local stem cell niches that maintain your skin, instead of just filling it in and smoothing over. Combined with micro-needling, deep wrinkles can also be modified with our cell-based therapy.

How you can use your own stem cells for aesthetic purposes

The technology has allowed reparative and preventative strategies to be developed with AdMSC-based therapy to support:

Scar remodelling

 All of these regenerative therapeutic strategies are based on stem cells from your own fat. Stromal vascular fraction (SVF) and pure AdMSC are typically employed by physicians.

SVF is rich in MSC and contains ±10% of these cells along with other cells found in adipose. Pure AdMSC is an isolated and characterised population of these stem cells.

What can be achieved with your stem cells and fat filler autografts in combination.

Restore definition to the nose and volume around the eyes, and in doing so address deep wrinkles

Use the slider to see before and after

Our aesthetic physicians will re-inject patient’s fat as a more natural and permanent method to enhance facial fullness, fill creases or build-up shallow contours. This is a departure from the ‘off the shelf’ fillers which others use, that last a few weeks before they’re broken-down and expelled by the body. Without the addition of your stem cells, only ±50% of fat injected will survive.

We also use fat autografts to improve the quality of larger aesthetic contouring procedures, including the breasts and buttocks.

In an autograft procedure, fat is processed into ‘nano fat’ to give the filler injectability and the required plasticity for modelling. Repeats of fat filler procedures maybe necessary as emulsified fat has to re-develop a scaffold (extracellular matrix) and blood supply (angiogenesis) to survive.

Deep wrinkles occur due to elastin degradation. A surgical facelift or botulinum toxin can transiently mask the appearance of deep wrinkles, but do not address the cause.

All of the cosmetic topicals you can buy do just one thing – from discounted face creams to a costly anti-aging serum – they plump the dead skin surface cells with water molecules; and in doing so, wick-away your natural moisturising factor.

In order to address deep wrinkles it’s necessary to asymmetrically break-down the degraded elastin in your skin for it to be regenerated by your cells. This means a course of needling or a pin-hole laser procedures with an aesthetic practitioner. Both rely on a ‘wound healing cascade’ to rebuild elastin, and our AdMSC based therapy can be used by the physician as a powerful anti-inflammatory to reduce downtime and improve tissue architecture remodelling.

Case study: 81 year-old skin tissue remodelling

We resolved and remodelled eight-years of skin tissue damage within 49 days.

81-year-old patient. Main (venous ulcer) wound 40mm x 35mm (14cm²). Pain score of 0/10 after 87 days. High tissue remodelling quality without scar fibrosis.

Above is an example of our autologous AdMSC-based therapy in chronic wound healing that highlights the speed of healing and quality of skin tissue architecture remodelling quality that’s possible even for an 81-year old. This is just one way we’ve used this powerful technology from your own stem cells, and it can greatly improve and repair the quality of your skin architecture.

The edges of a chronic wound are typically characterised by thick fibrotic scar tissue. Fibrosis is common to all scars and occur when there’s an ‘overload’ on the supporting tissue architecture to address the level and extent of wound damage.

A combination of medical aesthetic wound healing techniques like laser therapy along with our AdMSC-based therapeutic can be used to remodel and soften your scars.

Adding an AdMSC based therapy using your own stem cells for the procedure provides the additional tools for developing a graft scaffold and blood supply. This reduces the potential need for repeats and the results are more predictable. Alongside this procedure the other benefits of AdMSC based therapy can be achieved such as reduced downtime and superior skin remodelling.

Harnessing the regenerative capacity of AdMSC has created new opportunities to develop cell-based therapies for patients from acne and dermatitis, to autoimmune skin disorders. Of much interest has been recent work including topical applications for psoriasis vulgaris.

An advantage of topical AdMSC based therapies is that in certain circumstances they can penetrate the surface payer of the stratum corneum down to the basal layer. There is good reason to believe that in the nearer future AdMSC based topicals will become standard to dermatological therapy.