Your body is designed to repair itself – but perhaps your body finds itself unable to cope with its damage, due to an acute injury, a chronic condition, or simply with age. However, there’s an increasing number of natural solutions to this basic cellular repair problem.

Autologous (same donor-recipient) adipose derived mesenchymal stem cells (AdMSC) are found in abundance in your fat. AdMSC offer access to both current and future autologous stem cell based therapy that is safe and effective for various intractable conditions.


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02 STEM CELL BANKING

  • Regenerative Association laboratories in Switzerland and South Africa process autologous AdMSC from your fat that are the ‘cellular factories’ containing the agents your body’s own natural healing mechanisms.
  • ​Regenerative Association securely cryogenically store (aka ‘stem cell banking’) millions of your AdMSC, almost indefinitely; for release to a physician for your future use, or in case of immediate medical need.
  • ​Regenerative Association stem cell banking means you only have to donate a fat sample (5mL to 50mL) once in six easy steps.

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02 STEM CELL QUALITYRegenerative Association laboratories follow the highest clinical GMP standards to produce pharma-grade AdMSC stromal vascular fraction (SVF), that is an ‘AdMSC rich’ cellular tissue precursor to a pure AdMSC cell sample.

Our laboratory facilities in Switzerland and South Africa are Government agency accredited.

_53C9483 copy 2EU GMP Guidelines advise that a Grade A cleanroom facility has an ISO Class 05 work area within an ISO Class 07 room shell. We operate ISO Class 02 work areas within a ISO Class 05 room shell. Hence, our cell processing environment is 1,000-times particle-free (cleaner) than EU GMP Grade A.

We designed and maintain this high GMP cleanroom standard in collaboration with Total Clean Air, who are at the cutting-edge of cleanroom technology. We have also been early movers for new cleanroom technology that is ahead of GBP regulatory requirements such as Protak Scientific (decontamination validation) and Asymptote (cryogenics for advanced medicine).

​We operate an external quarantine as we do not accept any tissue samples onto our premises that are positive for transmissible disease.

02 STEM CELL SCIENCEFor the last 30-years stem cell medical science was based on ‘transplantation’ theory. For example, progenitor stem cells like AdMSC could be used like ‘off the shelf pharma drugs’. The idea was that stem cells would be directly injected to ‘engraft’ at the site of the damage, and would regeneratively form part of this tissue. Although mesenchymal stem cells were found to be safe, at doses higher than 10 million cells per kilogram of patient bodyweight, sufficient clinical efficacy eluded those conducting studies.

​Over 10-years ago we patented various methods to employ this elusive natural mechanism of action of autologous cells, based on years of research. We were concerned with Extracellular Vesicles (EVs) that comprise beneficial ‘intelligent’ particles, in particular exosomes. You will find exosomes in all of your body fluids. Exosomes are released by all cells 24-7-Life, including by stem cells, and are the key agent of action in any regenerative stem cell based therapy. EVs are ‘intelligent’ therapeutics as they find and fuse with the damaged cellular target to repair the tissue. Medical science can’t better what Mother Nature has provided – at least for now.

​You can find more about exosomes how they form and what they can do by visiting the International Society of Extracellular Vesicles; and, by watching their video “The Cell’s Secret Messengers

​Simply what this all means is that whether you’re having; an organ transplant; a nano-fat or micro-fat (aka emulsified fat) procedure; a fat-filler autograft; a bone marrow stem aspirate treatment; a stromal vascular fraction (SVF) treatment; or a whole (viable) stem cell transplant – they all rely on exosomes as an adjunctive or principle agent of action.

​Hence we think of all cell based treatments through the criteria of cells also being ‘cellular factories’ that produce EVs and other related agents, whether that occurs in-vivo or ex-vivo.